In 1929 the Sellersville and Perkasie Boards of Education got together and decided to provide a better education for students in the area. They decided to build a joint high school on the borders of the two districts. E. Williams Martin of Wilmington, Delaware was chosen to design the school.

The center of the original building is the border line of Perkasie and Sellersville. The front of the building features the names of each town: Sellersville on the left, Perkasie on the right.

In 1957 a new wing was added to the school to accommodate the increase in students. The firm of Micklewright and Mountford built 15 new classrooms, a second gymnasium and a cafeteria /kitchen complex (on the Sellersville end of the wing).

In 1965 another change occurred at the school when Pennridge Central Middle School was built in East Rockhill. The school changed names, and became known as Pennridge South Middle School. The attending students came from West Rockhill, Sellersville, and parts of Perkasie, Hilltown, and East Rockhill. Then ten years later, in 1975, another high school building was built, bringing different grades to South. From 1975 to now, it has been used for only seventh and eight graders.

In 1990, South was renovated to meet the demands of their growing number of students. The firm of Diseroad and Wolff of Hatfield, PA designed the new wing. New facilities included a gymnasium (capable of seating all students on bleachers for an event), locker rooms, a science pod, music suite, and eight more classrooms. Renovations of the original 1930's building and 1950's wing were also completed. The existing upper gymnasium was converted into a library. The construction process started in the summer of 1991 and ended in early 1993 - months before expected.

Many people view the school as a landmark for the community. It has seen generation after generation attend school there. Pennridge High School sporting events and graduation have been held on Lloyd Poppy Yoder Field (the stadium adjoining Penn South Middle School). This building has been changed many times, both the atmosphere and it's name, but its sense of tradition lives on.